Diarrhea Related Pathogen Nucleic Acid Detection Kit (PCR-Fluorescent Probe Method)

Product Information

Detection Target: Clostridioides difficile, Yersinia enterocolitica, Campylobacter coli, Campylobacter jejuni and Vibrio parahaemolyticus

Product Abbreviation: iFIND DP5

Cat. No. : 10T/box – 10210113A; 50T/box – 10210113B

iFIND infectious diarrhea bacteria five-item nucleic acid detection kit single-tube to check 5 common clinical pathogens, including Clostridium difficile, Yersinia yersinia parahaemolyticus, Campylobacter coli, Campylobacter jejunum detection, applicable population: used for auxiliary diagnosis of infectious diarrhea population.

Diarrhea Related Pathogen Nucleic Acid Detection Kit (PCR-Fluorescent Probe Method)

Current Situation

1. Disease Status: Bacterial diarrhea is a common intestinal infectious disease caused by various bacteria. Most pediatric patients have an acute onset, while only a portion have an insidious onset, with clinical manifestations ranging from mild to severe. Gastrointestinal symptoms (nausea, vomiting, abdominal distension, abdominal pain, diarrhea, etc.) are the main manifestations, among which the frequency of diarrhea can reach 10 to more than 20 times a day. This can lead to malnutrition in children, affecting their normal growth and development, and even endangering their lives and health in critical cases.
2. Disadvantages of Traditional Solutions: The gold standard for diagnosing infectious diarrhea is stool culture. Culture methods usually require a long time to yield results, leading to diagnostic delay and affecting early treatment. Traditional methods have low sensitivity in detecting low-concentration bacteria, making missed diagnoses likely.

iFIND Solution

1. Specific Advantages of the Cartridge and Instrument in Diarrheal Bacteria Detection
The entire process from sample addition to test result output takes only about 30 minutes, which significantly shortens the detection cycle compared with traditional culture methods (which usually take days or even weeks). This enables doctors to adjust treatment plans in a timely manner. Adopting quantitative real-time PCR (qPCR) technology, it can detect low-concentration bacterial nucleic acids with high sensitivity and good specificity. This allows the kit to detect low-level infections that may be missed by traditional culture methods, improving diagnostic accuracy. No complex sample processing steps are required, making it suitable for use in medical institutions at all levels and enhancing the accessibility and convenience of detection.
2. Purpose and Significance of the Cartridge
(1) Clarify Etiology and Guide Treatment: Clarifying the etiology to guide treatment is crucial. Bacterial diarrhea requires antibiotic treatment (e.g., quinolones for Shigella infection);
(2) Evaluate Disease Severity: Diarrhea caused by certain pathogens carries a higher risk. Pathogen detection helps doctors quickly identify high-risk patients and formulate more effective treatment plans.
(3) Trace Infection Source and Prevent Transmission: Infectious diarrhea is often contagious. Through pathogen detection, the type of pathogen can be determined, helping to trace the source of infection and take targeted prevention and control measures to prevent epidemic spread.
(4) Monitor Drug Resistance: Pathogen detection also helps analyze bacterial drug resistance. In recent years, the problem of bacterial drug resistance has become increasingly serious, especially the significant increase in resistance of certain intestinal pathogenic bacteria (such as Escherichia coli and Salmonella) to commonly used antibiotics. By detecting pathogenic bacteria, their sensitivity to antibiotics can be understood, thereby selecting appropriate therapeutic drugs and avoiding the spread of drug-resistant strains.