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Rocgene Nucleic Acid Extraction System

Routine Maintenance & Care

As core equipment in molecular diagnostics, Rocgene’s automated nucleic acid extraction systems have become indispensable lab assistants thanks to their high efficiency and stable performance. Standardized maintenance is critical to ensure long-term, reliable operation and accurate experimental results. Proper care extends instrument lifespan and safeguards data quality.

I. Daily Cleaning & Disinfection: Details Determine Experimental Success

1. Extraction Chamber Cleaning

● After each run, power off the instrument. Wipe the chamber with 75% ethanol‑soaked non‑woven fabric or absorbent cotton; avoid pouring liquids to prevent circuit damage. Once ethanol fully evaporates, activate the built‑in UV lamp for at least 30 minutes to thoroughly inactivate residual contaminants.

● If reagents are accidentally spilled, immediately clean the surface with a neutral detergent or 75% alcohol; avoid strong alkalis or organic solvents that may corrode instrument materials.

2. External Instrument Maintenance

● Regularly wipe the instrument casing with a mild neutral detergent to prevent dust buildup that impairs heat dissipation. Clean the screen only with water‑moistened non‑woven fabric; never use alcohol‑based liquids to avoid scratches.

II. Environmental & Operational Standards: Create Optimal Operating Conditions

1. Environmental Control

● Temperature: 10°C–40°C; Humidity: <80%; avoid dusty, humid, or direct‑sunlight environments.

● Ensure good ventilation around the instrument; keep the extraction chamber dry and free of condensation to protect circuit stability.

2. Power Management

● Use a stable AC 110–240V power supply; suspend operation if voltage is abnormal. For long‑term storage, unplug the power cord and cover with a dustproof hood.

III. Periodic Maintenance: Prevent Issues Before They Arise

1. Regular Dry Runs

● During idle periods, perform a dry run every 30 days to activate internal components and verify performance stability.

2. Deep Maintenance

● Magnetic Rod Care: If contaminated (e.g., without a magnetic rod sleeve), clean with mild detergent or 75% alcohol, dry thoroughly, and sterilize with UV light.

IV. Rocgene Service

Recently, a nucleic acid extraction system at a CDC in Hubei Province exhibited unstable sample concentrations and reduced extraction efficiency, compromising result accuracy and reliability. Following professional maintenance by Rocgene engineers, instrument performance improved significantly: extracted sample concentrations rose markedly, and results returned to stable levels. This case underscores the critical role of regular instrument maintenance in molecular testing.

Problem Identification: Abnormal Sample Concentrations Raise Concerns

During recent experiments, lab staff observed large fluctuations in nucleic acid extraction concentrations across identical sample batches, with some values far below expectations—even impairing subsequent PCR amplification efficiency. Initial troubleshooting ruled out reagent, procedural, and sample‑related issues, pointing to potential instrument performance deviations.

Professional Maintenance: Precise Troubleshooting & Resolution

Rocgene engineers responded promptly, conducting a comprehensive on‑site inspection and maintenance, including:

1. Key Component Cleaning & Calibration: Deep cleaning of magnetic bead adsorption modules, fluidic systems, robotic arms, and other core components to eliminate residual contamination affecting extraction efficiency.

2. Software Optimization: Updating instrument control programs and adjusting extraction parameters to ensure precision in bead binding, washing, and elution steps.

3. Consumable Compatibility Check: Verifying alignment between extraction kits and the instrument to avoid efficiency fluctuations from batch‑to‑batch consumable variations.

Post‑maintenance performance validation tests confirmed substantial improvements in nucleic acid extraction concentration and reduced inter‑batch variability, restoring the instrument to optimal working condition.

Photo: Our team performing cleaning and maintenance at a CDC customer site using the Easy Cleaner 7‑in‑1 Cleaning Kit (top left). For service requests, contact our after‑sales hotline: 010‑86229225 ext. 2 to schedule maintenance.

V. Brand Strength: Rocgene’s Commitment to Excellence

Rocgene (Beijing) Scientific Instruments Co., Ltd. (Rocgene), founded in 2016, is a core‑technology‑driven biotech enterprise established by scientists and business professionals.

Rocgene is dedicated to translating cutting‑edge life science research into clinically relevant medical products, developing proprietary research and molecular diagnostic solutions.

Recipient of numerous accolades including National High‑Tech Enterprise, Beijing “Specialized, Refined, Differential, Innovative” SME, and Zhongguancun High‑Tech Enterprise. Rocgene holds 4 Class III medical device registration certificates, 17 Class I medical device filings, 30 CE certifications, 4 US FDA clearances, 4 UK MHRA certifications, and 3 Indonesia NADFC approvals. Intellectual property includes 69 patents (42 invention, 13 utility model, 14 design) and 47 software copyrights. Products are exported to nearly 20 countries worldwide.

Our Xuzhou Intelligent Manufacturing Center features a 10,000‑sqm production base with automated lines, ensuring every instrument passes rigorous quality inspection. From R&D to after‑sales, Rocgene provides full‑lifecycle technical support for worry‑free lab operations.

ROCGENE SOLUTIONS

Instrumentation:

Accompanying Reagents:

Cleaning & Maintenance Kits:

Standardized maintenance is not only an “extension cord” for instrument lifespan but also a “lifeline” for reliable experimental data. With rigorous craftsmanship and attentive service, Rocgene empowers every nucleic acid extraction system with enduring performance, making research and diagnostics more efficient and precise. For technical support or customized maintenance plans, contact the Rocgene professional team.

After‑Sales Hotline: 010‑86229225 ext. 2 | Technical Support: 400‑860‑5168 ext. 4483
Official Website: http://www.rocgene.com